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Guilhian Leipnitz Selected Research

Hydroxylysine

11/2019Pathogenesis of brain damage in glutaric acidemia type I: Lessons from the genetic mice model.
1/2019Long Lasting High Lysine Diet Aggravates White Matter Injury in Glutaryl-CoA Dehydrogenase Deficient (Gcdh-/-) Mice.

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Guilhian Leipnitz Research Topics

Disease

9Mitochondrial Diseases (Mitochondrial Disease)
05/2023 - 08/2014
9Glutaric Acidemia I
11/2019 - 01/2007
7Ethylmalonic encephalopathy
12/2023 - 01/2012
6Nonketotic Hyperglycinemia
08/2023 - 08/2011
62-Hydroxyglutaricaciduria
01/2018 - 01/2002
5Inflammation (Inflammations)
12/2023 - 04/2017
4Neurodegenerative Diseases (Neurodegenerative Disease)
12/2023 - 12/2005
4Inborn Genetic Diseases (Disease, Hereditary)
08/2023 - 11/2009
4Brain Diseases (Brain Disorder)
08/2022 - 01/2017
4Ataxia (Dyssynergia)
06/2022 - 02/2013
4Body Weight (Weight, Body)
12/2019 - 06/2008
4Seizures (Absence Seizure)
11/2019 - 08/2012
4Short chain Acyl CoA dehydrogenase deficiency
08/2014 - 12/2002
3Maple Syrup Urine Disease
12/2023 - 01/2023
3Metabolic Diseases (Metabolic Disease)
12/2023 - 12/2012
3Gliosis
11/2023 - 01/2018
3Phenylketonurias (Phenylketonuria)
06/2021 - 03/2010
3Atrophy
01/2021 - 03/2010
3Hypermethioninemia
04/2019 - 01/2018
3Infections
09/2018 - 12/2015
3Refsum Disease (Refsum's Disease)
02/2013 - 08/2010
3Brain Injuries (Brain Injury)
01/2013 - 12/2005
3Glioma (Gliomas)
09/2010 - 01/2007
2Huntington Disease (Huntington's Disease)
05/2023 - 12/2005
2Wounds and Injuries (Trauma)
05/2023 - 01/2023
2Neuroinflammatory Diseases
01/2023 - 01/2022
2Methylmalonic acidemia
11/2022 - 07/2011
2Epilepsy (Aura)
11/2019 - 10/2003
2Cognitive Dysfunction
03/2019 - 10/2003
2Communicable Diseases (Infectious Diseases)
10/2017 - 06/2017
2Sulfite oxidase deficiency
01/2017 - 12/2013
2Cerebellar Ataxia (Dysmetria)
08/2013 - 02/2013
2Peroxisomal Disorders (Peroxisomal Disorder)
02/2013 - 03/2011
2Intellectual Disability (Idiocy)
12/2012 - 03/2010
2Medium chain acyl CoA dehydrogenase deficiency
08/2012 - 11/2007
2Hyperlysinemias (Hyperlysinemia)
02/2011 - 06/2009
2isovaleric Acidemia
03/2009 - 08/2008
1hypoglycemic encephalopathy
04/2024
1Virus Diseases (Viral Diseases)
04/2024
1Lysosomal Storage Diseases (Lysosomal Storage Disease)
03/2024
1Mucopolysaccharidosis II (Hunter Syndrome)
03/2024
1Diarrhea
12/2023

Drug/Important Bio-Agent (IBA)

15AcidsIBA
11/2023 - 01/2002
8Glutaryl-CoA DehydrogenaseIBA
08/2022 - 08/2015
7AntioxidantsIBA
06/2022 - 12/2005
7Lysine (L-Lysine)FDA Link
11/2019 - 06/2009
6Glycine (Aminoacetic Acid)FDA LinkGeneric
08/2023 - 08/2011
6BezafibrateIBA
05/2023 - 01/2017
6Reactive Oxygen Species (Oxygen Radicals)IBA
01/2023 - 09/2010
5EnzymesIBA
03/2024 - 06/2003
5SulfitesIBA
08/2023 - 12/2013
5Adenosine Triphosphatases (ATPase)IBA
07/2018 - 06/2009
5HHH syndromeIBA
08/2015 - 11/2009
4Glutathione (Reduced Glutathione)IBA
11/2022 - 12/2005
4ethylmalonic acid (ethylmalonate)IBA
01/2021 - 05/2003
4Tryptophan (L-Tryptophan)FDA Link
11/2019 - 06/2008
4Creatine Kinase (Creatine Phosphokinase)IBA
10/2017 - 06/2003
3Thiobarbituric Acid Reactive SubstancesIBA
12/2023 - 12/2005
3ThiosulfatesIBA
12/2023 - 12/2013
3Hydrogen Sulfide (Sulfide, Hydrogen)IBA
12/2023 - 01/2017
3Amino AcidsFDA Link
11/2023 - 02/2011
3Proteins (Proteins, Gene)FDA Link
08/2023 - 01/2018
3Sulfite OxidaseIBA
08/2023 - 11/2016
3S-Adenosylmethionine (Ademetionine)IBA
10/2021 - 07/2018
3Phenylalanine (L-Phenylalanine)FDA Link
06/2021 - 03/2010
3Fatty Acids (Saturated Fatty Acids)IBA
01/2019 - 08/2012
3OrnithineIBA
08/2013 - 11/2009
3homocitrullineIBA
08/2013 - 11/2009
3Phytanic AcidIBA
02/2013 - 08/2010
2Metformin (Glucophage)FDA LinkGeneric
04/2024 - 01/2022
2Branched-Chain Amino AcidsIBA
12/2023 - 01/2023
2Oxidoreductases (Dehydrogenase)IBA
12/2023 - 11/2023
2Sulfides (Thioethers)IBA
12/2023 - 01/2017
2Keto AcidsIBA
11/2023 - 01/2023
2molybdopterin (molybdenum cofactor)IBA
08/2023 - 01/2019
2Interleukin-6 (Interleukin 6)IBA
01/2023 - 01/2018
2Methylmalonic AcidIBA
11/2022 - 07/2011
23-methylglutaric acidIBA
06/2022 - 04/2020
2Phenylalanine Hydroxylase (Phenylalanine 4 Monooxygenase)IBA
06/2021 - 12/2019
2HMGA ProteinsIBA
04/2020 - 05/2019
2HydroxylysineIBA
11/2019 - 01/2019
2CatalaseIBA
11/2019 - 12/2012
2Brain-Derived Neurotrophic Factor (BDNF)IBA
03/2019 - 01/2018
2SilverIBA
09/2018 - 10/2017
2Electron Transport Complex IV (Cytochrome c Oxidase)IBA
01/2018 - 01/2002
2Quinolinic AcidIBA
11/2016 - 12/2005
2glutaric acidIBA
08/2015 - 01/2007
2AmmoniaIBA
08/2013 - 12/2012
2isovaleric acidIBA
03/2009 - 08/2008
2KynurenineIBA
01/2007 - 12/2005
1Antiviral Agents (Antivirals)IBA
04/2024
1InterferonsIBA
04/2024
1CytokinesIBA
04/2024
1GlycosaminoglycansIBA
03/2024
1Iduronic Acid (Iduronate)IBA
03/2024
1Memantine (Namenda)FDA Link
12/2023
1AcetylcholinesteraseIBA
12/2023
12',7'-dichlorofluoresceinIBA
12/2023

Therapy/Procedure

4Therapeutics
05/2023 - 06/2015
3Subcutaneous Injections
01/2018 - 06/2008